Separation Scientist / Senior Separation Scientist

Job Title: Separation Scientist / Senior Separation Scientist

Locations: Cambridge, UK

Salary: Competitive + Excellent Employee Benefits!

Applications Deadline: July 14

Introduction to the role:

At AstraZeneca, innovation is more than just research. As one of the world's leading pharmaceutical companies, we’re focused on providing innovative, effective medicines that make a real difference in important areas of healthcare. We’re investing in a state-of-the-art research centre and corporate headquarters at the Cambridge Biomedical Campus, and we aim to bring together the finest talent in business and academia. Join us, and you’ll be part of a brand-new vision for a critical industry, making a difference world-wide.

Oncology is a core therapy area and growth platform at AstraZeneca and our vision is to deliver life-changing medicines that improve outcomes for patients most in need. As part of Oncology Chemistry, world leading group with a history of delivery and innovation, Analytical and Structural Chemistry plays an important role in advancing new oncology drug projects to make a positive impact on changing patients’ lives. The team operates in a highly cross disciplinary environment in close collaboration with scientists from the Chemistry, Computational Chemistry, Bioscience, DMPK and Pharmaceutical Science departments to advance the Oncology project pipeline.

Accountabilities:

As SeparationScientist / Senior Separation Scientist, you will be part of a team of highly motivated scientists contributing to chiral and achiral analysis, preparative separation and quality control of new chemical entities. You will be delivering through hands-on experimentation to ensure that critical compounds are isolated and characterised within challenging deadlines. As a member of this team, you will be closely working with synthetic, medicinal and computational chemists to progress chemistry objectives in projects at various stages of drug discovery. 

At Senior Scientist level, you would be expected tolead local scientific and technology development projectsand/or contribute to global initiatives toensure that ourseparation science capabilities meet the future needs of AstraZeneca’s drug discovery projects.

You will be expected to have effective levels of communication and scientific drive, co-ordinating effectively with the other members of the analytical and synthesis teams to drive sample progression.

Experience and technical knowledge of chromatographic separations, particularly preparative separations would be an advantage, however, full training will be provided.

Responsibilities of the role

• Provide hands-on chiral and achiral separation sciencesupport to drug discovery chemistry using state-of-the art chromatographic instrumentation

• Develop methods foranalysis and purification of novel compounds using a range of chromatographic techniques (HPLC, UPLC and SFC)

• Ensure performance and data quality of analytical instrumentation and automation platforms

• Pro-actively enablethe development of advanced methodologies and/or automated solutions to increase lab capability and/or productivity. Work with the team to suggestprocess, technology and methodologyimprovements.

• Contribute to a vibrant and ambitious organization focused on innovation & project delivery; collaborating closely with scientists across the discovery organization

• Participate in Oncology ChemistryactivitiessuchasSHE, training, recruitment etc.

Skills and experience

• PhD / BSc in Chemistry or Analytical Chemistry

• Good knowledge of analytical and/or preparative chromatographic techniques (HPLC, SFC, HPLC-MS) including method development and instrument troubleshooting

• Detailed understanding of the use ofanalyticaltechniques to solve complex scientific questions

• A track recordof applyinganalytical chemistry techniques to solve scientific problems

• Knowledge ofpharmaceutical drug discovery

• Ability to work in multidisciplinary team / project / function 

• Excellent communication skills

• First-rate time management skills, forward planning and delivery focus, leading to good team working and a high level of self and team delivery

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, gender or gender orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.